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Recent News
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(11/09/09) Prof. Sean Smith and his group will be playing a major in an initiative to secure the power grid. Read more here. |
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(11/08/09) Prof. Hany Farid finds that iconic Oswald photo was not faked. Read more here. |
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(11/08/09) Prof. Tanzeem Choudhury has been named a TEDIndia Fellow for 2009. Read more here. |
Recent Technical Reports
- September 2009: Katana: A Hot Patching Framework for ELF Executables
- October 2010: Detecting Photographic Composites of Famous People
- September 2009: Activity-Aware Electrocardiogram-based Passive Ongoing Biometric Verification
- August 2009: Semantic and Visual Encoding of Diagrams
- July 2009: Distributed Monitoring of Conditional Entropy for Network Anomaly Detection
Featured Research
Multimodal Protein Structure
How is oxygen carried around in blood, how are invaders recognized by cells, and how is food digested? Answers to these and other questions about the molecular machinery of the cell (and potentially how to modify it) center on analysis of three-dimensional protein structures. We are embedding computation as a core component of structural studies, planning experiments to maximize the information gained, interpreting the results so as to characterize remaining uncertainty, and iterating. For example, reasoning by analogy to other proteins, we can predict possible models for a new protein (see figure). Then we can analyze their differences (e.g., distances between landmarks, overall envelopes, surface vs. core locations) and optimize experimental probes for these differences, employing "multimodal" sets of probes to overcome the noise and sparsity characteristics of any individual experimental type.